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Ovarian Epithelial Cancer |
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Ovarian epithelial cancer is a disease in which malignant (cancer) cells form in the tissue covering the ovary. The ovaries are a pair of organs in the female reproductive system. They are located in the pelvis, one on each side of the uterus (the hollow, pear-shaped organ where a fetus grows). Each ovary is about the size and shape of an almond. The ovaries produce eggs and female hormones (chemicals that control the way certain cells or organs function). Ovarian epithelial cancer is one type of cancer that affects the ovary. Women who have a family history of ovarian cancer are at an increased risk of developing ovarian cancer. Women who have one first-degree relative (mother, daughter, or sister) with ovarian cancer are at an increased risk of developing ovarian cancer. This risk is higher in women who have one first-degree relative and one second-degree relative (grandmother or aunt) with ovarian cancer. This risk is even higher in women who have two or more first-degree relatives with ovarian cancer. Some ovarian cancers are caused by inherited gene mutations (changes). The genes in cells carry the hereditary information that is received from a person’s parents. Hereditary ovarian cancer makes up approximately 5% to 10% of all cases of ovarian cancer. Three hereditary patterns have been identified: ovarian cancer alone, ovarian and breast cancers, and ovarian and colon cancers. Tests that can detect mutated genes have been developed. These genetic tests are sometimes done for members of families with a high risk of cancer. Women with an increased risk of ovarian cancer may consider surgery to prevent it. Some women who have an increased risk of ovarian cancer may choose to have a prophylactic oophorectomy (the removal of healthy ovaries so that cancer cannot grow in them). It is not known if this procedure prevents ovarian cancer. Possible signs of ovarian cancer include pain or swelling in the abdomen.
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